DNA Structure – a new look

Dr. Giacomo Cavalli asked us to create an animation detailing his lab and collaborating labs’ work on unraveling the true structure of DNA, which doesn’t form symmetrical helical supercoils of DNA and histones, but rather, forms loosely bound “clutches” that then assemble into larger unstructured masses.

DNA Script – SYNTAX

Arkitek Scientific created this animation describing DNA Script’s flagship machine, the SYNTAX, an extremely easy-to-use platform for creating DNA probes in rapid fashion.

Evelo Biosciences

A novel approach Evelo Biosciences is taking toward tackling disease, utilizing beneficial bacteria to deliver medicines via the gastrointestinal tract.

Unifarco Biomedical – Ceramol

Unifarco Biomedical asked us to create an animation detailing the mechanisms within the skin, as well as highlighting their novel topical formulation for treating atopic dermatitis (AD).

Degruyter/Energy Today Journal

Arkitek created this introductory animation for the re-launch of the Energy Today journal, published by DeGruyter.

Nature Immunology – Immunology of the Rheumatoid Joint

This piece dives into the role of various cytokines that drive the progression of rheumatoid arthritis.

Nature Reviews Drug Discovery – Psoriasis and Beyond

Another in a series about immunology for Nature Reviews Drug Discovery. It describes the mechanisms underlying psoriasis, and how the body’s immunological arsenal turns on itself.

Rive Technology – Molecular Highway

Rive Technologies’ technology solved the problem of over-cracking hydrocarbons during the purification process by creating larger pores within zeolite crystals.

Stratos Genomics – SBX

Stratos Genomics’ method utilized reporters sandwiched between bases. The DNA chain was then read through nanopores at high speed, achieving extreme accuracy.

SISCAPA Assay Technologies

SISCAPA Assay Technologies developed a novel method for detecting trace peptides in blood samples by comparing wild and labeled peptides using mass spec techniques.

Allen Institute for Brain Research

Arkitek designed and produced this piece for the Allen Institute for their TED talk in 2011.

Nautilus Biotechnology

This animation explains Nautilus’ unique method for identifying and quantifying individual proteins on a chip using fluorescence. Up to 10 million distinct proteins are tethered to a DNA substrate. Multiple passes using specific reagent probes bind to specific proteins, and the fluorescent tag is recorded using a high-density camera. Individual images, when processed, identify the labeled proteins on the chip.

LongitueDX

This animation describes SISCAPA’s Assay Technologies’ method for specific peptide quantitation, using labeled peptides as an internal standard.

Boston Biomedical – STAT3

Created for Boston Biomedical to help explain the role of STAT3 in tumor production.

Innonix – Respokare mask

Innonix, makers of Respokare masks, approached us to help illustrate their new anti-pollution mask, and what differentiates it from other masks.

Nature Immunology – Immunology of the Gut

This animation introduces the key cells and molecular participants involved in gut immuno-homeostasis and disease.

Immunomic Therapeutics

Its novel technology harnesses MHC-II pathways to re-educate the immune system to respond to allergenic proteins as if they were pathogens. This animation describes their method.

ABSciex – SWATH

With ABSciex’ novel SWATH technology, one can gather ALL the information available in a mass spec sample, and can access that data later to compare different peptides in a sample.

ABSciex – Sensibility 6500 Series

This was another in a series of animations done for ABSciex to illuminate the features of their latest mass spectrometer, the 6500 Series.

Beckman-Coulter – CESI 8000

Beckman asked us to create an animation detailing their flagship product, which utilizes high efficiency, high resolution electrophoretic separation of charged and polar molecules.

Exiqon – LNA

DNA switches between the S and N conformation. By locking the DNA into the N conformation using a methylene bridge the probes can withstand high temperatures, increasing specificity.

Unifarco Biomedical – Ceramage

This animation details the mechanisms involved in skin aging, called inflamaging, and the ways in which Unifarco Biomedical’s new product, Ceramage, combats the effects of aging.

Fred Hutchison Cancer Research Center

Fred Hutchison Cancer Research Center engaged Arkitek Scientific to create an animation for middle school kids to teach them about what mRNA vaccines are, how they are produced, and specifically how the current mRNA vaccines target COVID-19

ProMed – Rebagit

This animation explains the mechanism behind ProMed’s novel product Rebagit, which targets gut dysbiosis by restoring the tight junctions between cells lining the gut.

Allen Institute for Brain Research

A conceptual animation done for the Allen Institute for Brain Research, showing the formation of biological systems within a Zebrafish.

Boston Biomedical – MCL-1

Boston Biomedical asked us to create this animation to describe the role of MCL-1 in the inhibition of apoptosis in myeloid cell leukemia 1.

Scripps Institute of Oceanography – Atmospheric Rivers

Scripps Institute of Oceanography asked us to create an animation that explains what atmospheric rivers are, and how they impact the US West Coast and beyond.

Nature Reviews Genetics – RNAi Interference

This revised animation of the popular RNAi animation build on the original version we did for Nature. Dr. Craig Mello, Nobel Laureate for Medicine in 2006, consulted on this project.

Nature Immunology – Immunology of the Lung

This animation introduces the cells and immunological processes underlying the initiation and pathogenesis of asthma.

Nature Immunology – Immunology of the Skin

This animation explains the skin’s function as a protective barrier between us and the outside world. Without its arsenal of protective immune cells, we wouldn’t last long.

Nature Drug Discovery – Targeting Cancer Cell Metabolism

This animation focuses on how cancer cells metabolize glucose at such a high rate, turning ATP production on its head by converting pyruvate to lactate instead of using it to create more ATP.

ABSciex – Crane2 4500 Mass Spectrometer

One of several biomedical devices we’ve animated for Sciex, this animation explains the features of the 4500 mass spectrometer.

General Fusion

General Fusion uses pistons driven by compressed gas to achieve fusion of injected plasma.

Clients

Biomedical Animation

Nautilus Biomedical

Merck Pharmaceuticals

General Fusion

Nature Immunology

Fred Hutchison Cancer Research Center

Institute of Human Genetics CNRS

DNA Script

Immunomic Therapeutics

Pfizer Pharmaceuticals

Nature Reviews Rheumatology

Beckman Coulter

Universitat Wien

Scripps Institute of Oceanography

Scitable by Nature Education

LongitudeDX

Oxford-Brookes University

Allen Institute for Brain Research

Riken Center for Developmental Biology

Roche Pharmaceuticals

Sciex

Evelo Biosciences

Nature Reviews Genetics

The Franklin Museum

Pro Med CS

Unifarco Biomedical

Siscapa Assay Technologies

Nature Reviews Immunology

Energy Today Journal – DeGruyter

McGraw Hill Publishing

Cedars-Sinai

Boston Biomedical

Nature Reviews Drug Discovery

Massachusetts General Hospital

Stratos Genomics

University of Warsaw

Mississippi Museum of Natural HIstory

Innonix

Viral Defense Inc.

Life Technologies

University of British Columbia

Terrapower

National Institutes of Health

University of Denmark

Acucela Inc.

Degruyter/Energy Today

ProQura

Rive Technology

Exiqon

Large Scale Biology Corporation

Washington Global Health Alliance

Bellevue College

Nissan

Oregon Public Broadcasting

GnuBio

Ascent Pharmaceuticals

University of Washington – Genetics

Microsoft

AT&T